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Normalizing single-cell RNA sequencing data: Challenges and opportunities

Single-cell transcriptomics is becoming an important component of the molecular biologist’s toolkit. A critical step when analyzing this type of data is normalization. However, normalization is typically performed using methods developed for bulk RNA sequencing or even microarray data, whose suitabi...

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Bibliografiska uppgifter
I publikationen:Nat Methods
Huvudupphovsmän: Vallejos, Catalina A., Risso, Davide, Scialdone, Antonio, Dudoit, Sandrine, Marioni, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549838/
https://ncbi.nlm.nih.gov/pubmed/28504683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4292
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