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Normalizing single-cell RNA sequencing data: Challenges and opportunities
Single-cell transcriptomics is becoming an important component of the molecular biologist’s toolkit. A critical step when analyzing this type of data is normalization. However, normalization is typically performed using methods developed for bulk RNA sequencing or even microarray data, whose suitabi...
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| 發表在: | Nat Methods |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5549838/ https://ncbi.nlm.nih.gov/pubmed/28504683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4292 |
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