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Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference

Novel single-cell transcriptome sequencing assays allow researchers to measure gene expression levels at the resolution of single cells and offer the unprecendented opportunity to investigate at the molecular level fundamental biological questions, such as stem cell differentiation or the discovery...

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Bibliografiske detaljer
Udgivet i:F1000Res
Main Authors: Perraudeau, Fanny, Risso, Davide, Street, Kelly, Purdom, Elizabeth, Dudoit, Sandrine
Format: Artigo
Sprog:Inglês
Udgivet: F1000Research 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558107/
https://ncbi.nlm.nih.gov/pubmed/28868140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12122.1
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