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Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference

Novel single-cell transcriptome sequencing assays allow researchers to measure gene expression levels at the resolution of single cells and offer the unprecendented opportunity to investigate at the molecular level fundamental biological questions, such as stem cell differentiation or the discovery...

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Détails bibliographiques
Publié dans:F1000Res
Auteurs principaux: Perraudeau, Fanny, Risso, Davide, Street, Kelly, Purdom, Elizabeth, Dudoit, Sandrine
Format: Artigo
Langue:Inglês
Publié: F1000Research 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558107/
https://ncbi.nlm.nih.gov/pubmed/28868140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12122.1
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