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Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference

Novel single-cell transcriptome sequencing assays allow researchers to measure gene expression levels at the resolution of single cells and offer the unprecendented opportunity to investigate at the molecular level fundamental biological questions, such as stem cell differentiation or the discovery...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Perraudeau, Fanny, Risso, Davide, Street, Kelly, Purdom, Elizabeth, Dudoit, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558107/
https://ncbi.nlm.nih.gov/pubmed/28868140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12122.1
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