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Evolution of new regulatory functions on biophysically realistic fitness landscapes

Gene expression is controlled by networks of regulatory proteins that interact specifically with external signals and DNA regulatory sequences. These interactions force the network components to co-evolve so as to continually maintain function. Yet, existing models of evolution mostly focus on isola...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Friedlander, Tamar, Prizak, Roshan, Barton, Nicholas H., Tkačik, Gašper
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548793/
https://ncbi.nlm.nih.gov/pubmed/28790313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00238-8
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