IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and -negative bacterial pneumonia

Interleukin-36γ (IL-36γ) is a member of novel IL-1-like proinflammatory cytokine family that are highly expressed in epithelial tissues and several myeloid-derived cell types. Little is known about the role of the IL-36 family in mucosal immunity, including lung anti-bacterial responses. We used mur...

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Udgivet i:Mucosal Immunol
Main Authors: Kovach, M A, Singer, B, Martinez-Colon, G, Newstead, M W, Zeng, X, Mancuso, P, Moore, T A, Kunkel, S L, Peters-Golden, M, Moore, B B, Standiford, T J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Orginal Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548659/
https://ncbi.nlm.nih.gov/pubmed/28176791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.130
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