IL-36 Receptor Deletion Attenuates Lung Injury and Decreases Mortality in Murine Influenza Pneumonia

Influenza virus causes a respiratory disease in human that can progress to lung injury with fatal outcome. The interleukin (IL)-36 cytokines are newly described IL-1 family cytokines that promote inflammatory responses via binding to the IL-36 receptor (IL-36R). The mechanism of expression and the r...

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Publicado en:Mucosal Immunol
Autores principales: Aoyagi, Tetsuji, Newstead, Michael W., Zeng, Xianying, Kunkel, Steven L., Kaku, Mitsuo, Standiford, Theodore J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471142/
https://ncbi.nlm.nih.gov/pubmed/27966554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.107
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