Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia

Influenza virus is a common cause of respiratory infection and morbidity, which is often due to deleterious host immune responses directed against the pathogen. We investigated the role of IL-1 receptor-associated kinase-M (IRAK-M), an inhibitor of MyD88-dependent TLR signaling, in modulating the in...

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Main Authors: Seki, Masafumi, Kohno, Shigeru, Newstead, Michael W., Zeng, Xianying, Bhan, Urvashi, Lukacs, Nicholas W., Kunkel, Steven L., Standiford, Theodore J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995366/
https://ncbi.nlm.nih.gov/pubmed/20042589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901709
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