Cooperative Interactions between TLR4 and TLR9 Regulate Interleukin 23 and 17 Production in a Murine Model of Gram Negative Bacterial Pneumonia

Toll like receptors play an important role in lung host defense against bacterial pathogens. In this study, we investigated independent and cooperative functions of TLR4 and TLR9 in microbial clearance and systemic dissemination during Gram-negative bacterial pneumonia. To access these responses, wi...

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Autori principali: Bhan, Urvashi, Ballinger, Megan N., Zeng, Xianying, Newstead, Michael J., Cornicelli, Matthew D., Standiford, Theodore J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845620/
https://ncbi.nlm.nih.gov/pubmed/20360853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009896
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