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Cathelicidin Related Antimicrobial Peptide is Required for Effective Lung Mucosal Immunity in Gram-negative Bacterial Pneumonia

Cathelicidins are a family of endogenous antimicrobial peptides that exert diverse immune functions, including both direct bacterial killing and immunomodulatory effects. In this study, we examined the contribution of the murine cathelicidin, CRAMP, to innate mucosal immunity in a mouse model of Gra...

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Detalhes bibliográficos
Main Authors: Kovach, Melissa A., Ballinger, Megan N., Newstead, Michael W., Zeng, Xianying, Bhan, Urvashi, Yu, Fu-shin, Moore, Bethany B., Gallo, Richard L., Standiford, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566644/
https://ncbi.nlm.nih.gov/pubmed/22634613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103196
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