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Flagellin Stimulates Protective Lung Mucosal Immunity: Role of Cathelicidin Related Antimicrobial Peptide (CRAMP)

Toll like receptors are required for generation of protective lung mucosal immune responses against microbial pathogens. In this study, we evaluated the effect of the TLR5 ligand flagellin on stimulation of antibacterial mucosal immunity in a lethal murine Pseudomonas aeruginosa (PA) pneumonia model...

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Autors principals: Yu, Fu-shin, Cornicelli, Matthew D., Kovach, Melissa A., Newstead, Michael W., Zeng, Xianying, Kumar, Ashok, Gao, Nan, Yoon, Sang Gi, Gallo, Richard L., Standiford, Theodore J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038689/
https://ncbi.nlm.nih.gov/pubmed/20566829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000509
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