Interferon Regulatory Factor-1 in Flagellin-Induced Reprogramming: Potential Protective Role of CXCL10 in Cornea Innate Defense Against Pseudomonas aeruginosa Infection

PURPOSE. We previously showed that pre-exposure of the cornea to Toll-like receptor (TLR)5 ligand flagellin induces strong protective innate defense against microbial pathogens and hypothesized that flagellin modulates gene expression at the transcriptional levels. Thus, we sought to determine the r...

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Main Authors: Yoon, Gi Sang, Dong, Chen, Gao, Nan, Kumar, Ashok, Standiford, Theodore J., Yu, Fu-Shin X.
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832217/
https://ncbi.nlm.nih.gov/pubmed/24130180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12453
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