Redundant and Cooperative Interactions between TLR5 and NLRC4 in Protective Lung Mucosal Immunity against Pseudomonas aeruginosa

Flagellin is the major structural component of flagella expressed by Pseudomonas aeruginosa (PA) and other bacteria. This protein has been shown to activate the Toll-like receptor TLR5 and the Nod-like receptor Nlrc4/Ipaf, culminating in the expression of innate cytokines and antimicrobial molecules...

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Pubblicato in:J Innate Immun
Autori principali: Tolle, Leslie, Yu, Fu-shin, Kovach, Melissa A., Ballinger, Megan N., Newstead, Michael W., Zeng, Xianying, Nunez, Gabriel, Standiford, Theodore J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348217/
https://ncbi.nlm.nih.gov/pubmed/25402425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000367790
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