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TLR4-dependent GM-CSF protects against lung injury in Gram-negative bacterial pneumonia

Toll-like receptors (TLRs) are required for protective host defense against bacterial pathogens. However, the role of TLRs in regulating lung injury during Gram-negative bacterial pneumonia has not been thoroughly investigated. In this study, experiments were performed to evaluate the role of TLR4 i...

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Autors principals: Standiford, Louis R., Standiford, Theodore J., Newstead, Michael J., Zeng, Xianying, Ballinger, Megan N., Kovach, Melissa A., Reka, Ajaya K., Bhan, Urvashi
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311511/
https://ncbi.nlm.nih.gov/pubmed/22160309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00415.2010
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