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Beyond transcription factors: how oncogenic signaling reshapes the epigenetic landscape
Cancer, once thought to be caused largely by genetic alterations, is now considered to be a mixed genetic and epigenetic disease. The epigenetic landscape, which is dictated by covalent DNA and histone modifications, is profoundly altered in transformed cells. These abnormalities may arise due to mu...
में बचाया:
| में प्रकाशित: | Nat Rev Cancer |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548460/ https://ncbi.nlm.nih.gov/pubmed/27220480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2016.41 |
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