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Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation–inactivation cycle
IFN-γ treatment of cells leads to tyrosine phosphorylation of signal transducer and activator of transcription (STAT) 1 followed by dimerization through a reciprocal Src homology 2–phosphotyrosine interaction near the –COOH end of each monomer, forming a parallel structure that accumulates in the nu...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15753310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0501063102 |
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