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Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation–inactivation cycle
IFN-γ treatment of cells leads to tyrosine phosphorylation of signal transducer and activator of transcription (STAT) 1 followed by dimerization through a reciprocal Src homology 2–phosphotyrosine interaction near the –COOH end of each monomer, forming a parallel structure that accumulates in the nu...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554839/ https://ncbi.nlm.nih.gov/pubmed/15753310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501063102 |
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