Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

Microglia are the primary innate immune cell type in the brain, and their dysfunction has been linked to a variety of central nervous system disorders. Human microglia are extraordinarily difficult to obtain for experimental investigation, limiting our ability to study the impact of human genetic va...

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Detalhes bibliográficos
Publicado no:ASN Neuro
Main Authors: Amos, Peter J., Fung, Susan, Case, Amanda, Kifelew, Jerusalem, Osnis, Leah, Smith, Carole L., Green, Kevin, Naydenov, Alipi, Aloi, Macarena, Hubbard, Jesse J., Ramakrishnan, Aravind, Garden, Gwenn A., Jayadev, Suman
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548325/
https://ncbi.nlm.nih.gov/pubmed/28683563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091417716610
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