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Presenilin 2 influences miR146 level and activity in microglia

Microglia, the resident innate immune cells of the CNS, are the primary defenders against microbes and critical to CNS remodeling. Dysregulation of microglial behavior can lead to unchecked pro-inflammatory activity and subsequent neurodegeneration. The molecular mechanisms leading to chronic inflam...

詳細記述

保存先:
書誌詳細
出版年:J Neurochem
主要な著者: Jayadev, Suman, Case, Amanda, Alajajian, Betty, Eastman, Alison J., Möller, Thomas, Garden, Gwenn A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346352/
https://ncbi.nlm.nih.gov/pubmed/23952003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12400
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