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Presenilin 2 influences miR146 level and activity in microglia

Microglia, the resident innate immune cells of the CNS, are the primary defenders against microbes and critical to CNS remodeling. Dysregulation of microglial behavior can lead to unchecked pro-inflammatory activity and subsequent neurodegeneration. The molecular mechanisms leading to chronic inflam...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Jayadev, Suman, Case, Amanda, Alajajian, Betty, Eastman, Alison J., Möller, Thomas, Garden, Gwenn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346352/
https://ncbi.nlm.nih.gov/pubmed/23952003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12400
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