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Presenilin 2 influences miR146 level and activity in microglia
Microglia, the resident innate immune cells of the CNS, are the primary defenders against microbes and critical to CNS remodeling. Dysregulation of microglial behavior can lead to unchecked pro-inflammatory activity and subsequent neurodegeneration. The molecular mechanisms leading to chronic inflam...
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出版年: | J Neurochem |
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主要な著者: | , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346352/ https://ncbi.nlm.nih.gov/pubmed/23952003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12400 |
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