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AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34(+) cells, allowing nerve growth factor-induced expansion
The AML1-ETO fusion protein, generated by the t(8;21) in acute myeloid leukemia (AML), exerts dominant-negative functions and a variety of gains of function, including a positive effect on the growth of primary human CD34(+) hematopoietic stem/progenitor cells. We now show that AML1-ETO expression u...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554792/ https://ncbi.nlm.nih.gov/pubmed/15731354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404701102 |
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