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Intratumoral STING activation with T-cell checkpoint modulation generates systemic antitumor immunity
Coordinated manipulation of independent immune regulatory pathways in the tumor microenvironment – including blockade of T-cell checkpoint receptors and reversal of suppressive myeloid programs – can render aggressive cancers susceptible to immune rejection. Elevated toxicity associated with combina...
Gorde:
| Argitaratua izan da: | Cancer Immunol Res |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547907/ https://ncbi.nlm.nih.gov/pubmed/28674082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0049 |
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