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TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma
Tumors that lack pre-existing immune infiltration respond poorly to T cell checkpoint blockade immunotherapy. These cancers often surround themselves with high densities of suppressive myeloid stroma while excluding immunostimulatory dendritic cells. Tumor-resident myeloid cells and selected lymphoc...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6880482/ https://ncbi.nlm.nih.gov/pubmed/31771649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0811-x |
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