TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma

Tumors that lack pre-existing immune infiltration respond poorly to T cell checkpoint blockade immunotherapy. These cancers often surround themselves with high densities of suppressive myeloid stroma while excluding immunostimulatory dendritic cells. Tumor-resident myeloid cells and selected lymphoc...

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Podrobná bibliografie
Vydáno v:J Immunother Cancer
Hlavní autoři: Reilley, Matthew J., Morrow, Brittany, Ager, Casey R., Liu, Arthur, Hong, David S., Curran, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880482/
https://ncbi.nlm.nih.gov/pubmed/31771649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0811-x
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