MIF inhibition as a strategy for overcoming resistance to immune checkpoint blockade therapy in melanoma

Immune checkpoint blockade (ICB) has demonstrated an impressive outcome in patients with metastatic melanoma, yet, durable complete response; even with Ipilimumab/Nivolumab combo are under 30%. Primary and acquired resistance in response to ICB is commonly due to a tumor immune escape mechanism dict...

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Détails bibliographiques
Publié dans:Oncoimmunology
Auteurs principaux: de Azevedo, Ricardo A., Shoshan, Einav, Whang, Shanzhi, Markel, Gal, Jaiswal, Ashvin R., Liu, Arthur, Curran, Michael A., Travassos, Luiz R., Bar-Eli, Menashe
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733907/
https://ncbi.nlm.nih.gov/pubmed/33344042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1846915
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