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A distinct subpopulation of CD25(−) T-follicular regulatory cells localizes in the germinal centers

T-follicular helper (Tfh) cells differentiate through a multistep process, culminating in germinal center (GC) localized GC-Tfh cells that provide support to GC-B cells. T-follicular regulatory (Tfr) cells have critical roles in the control of Tfh cells and GC formation. Although Tfh-cell differenti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wing, James Badger, Kitagawa, Yohko, Locci, Michela, Hume, Hannah, Tay, Christopher, Morita, Takayoshi, Kidani, Yujiro, Matsuda, Kyoko, Inoue, Takeshi, Kurosaki, Tomohiro, Crotty, Shane, Coban, Cevayir, Ohkura, Naganari, Sakaguchi, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547636/
https://ncbi.nlm.nih.gov/pubmed/28698369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705551114
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