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Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease
CONTEXT: Remission failure following transsphenoidal surgery in Cushing disease (CD) from pituitary corticotroph tumors (CtTs) remains clinically challenging. Histone deacetylase inhibitors (HDACis) are antitumor drugs approved for clinical use, with the potential to affect adrenocorticotropin hormo...
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Publicado no: | J Clin Endocrinol Metab |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Endocrine Society
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546859/ https://ncbi.nlm.nih.gov/pubmed/28505327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-00464 |
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