Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease

CONTEXT: Remission failure following transsphenoidal surgery in Cushing disease (CD) from pituitary corticotroph tumors (CtTs) remains clinically challenging. Histone deacetylase inhibitors (HDACis) are antitumor drugs approved for clinical use, with the potential to affect adrenocorticotropin hormo...

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Detaylı Bibliyografya
Yayımlandı:J Clin Endocrinol Metab
Asıl Yazarlar: Lu, Jie, Chatain, Grégoire P., Bugarini, Alejandro, Wang, Xiang, Maric, Dragan, Walbridge, Stuart, Zhuang, Zhengping, Chittiboina, Prashant
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2017
Konular:
Clinical Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546859/
https://ncbi.nlm.nih.gov/pubmed/28505327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-00464
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