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EXTH-12. REPURPOSING PROPRANOLOL AS AN ANTI-TUMOR AGENT FOR VON HIPPEL-LINDAU DISEASE

INTRODUCTION: von Hippel-Lindau disease (VHL) is a tumor predisposition syndrome characterized by the development of CNS hemangioblastomas (VHL-HB) and renal cell carcinomas (RCC) due to hypoxia inducible factor activation. Due to a lack of effective medical therapies for VHL, HBs/RCCs may lead to s...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Shepard, Matthew, Bugarini, Alejandro, Zhang, Qi, Zhuang, Zhengping, Chittiboina, Prashant
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692407/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.307
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