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Intracellular trafficking of new anticancer therapeutics: antibody–drug conjugates
Antibody–drug conjugate (ADC) is a milestone in targeted cancer therapy that comprises of monoclonal antibodies chemically linked to cytotoxic drugs. Internalization of ADC takes place via clathrin-mediated endocytosis, caveolae-mediated endocytosis, and pinocytosis. Conjugation strategies, endocyto...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546728/ https://ncbi.nlm.nih.gov/pubmed/28814834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S135571 |
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