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Intracellular delivery and trafficking dynamics of a lymphoma-targeting antibody-polymer conjugate

Ratiometric fluorescence and cellular fractionation studies were employed to characterize the intracellular trafficking dynamics of antibody-poly(propylacrylic acid) (PPAA) conjugates in CD22+ RAMOS-AW cells. The HD39 monoclonal antibody (mAb) directs CD22-dependent, receptor-mediated uptake in huma...

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Detalhes bibliográficos
Main Authors: Berguig, Geoffrey Y., Convertine, Anthony J., Shi, Julie, Palanca-Wessels, Maria Corinna, Duvall, Craig L., Pun, Suzie H., Press, Oliver W., Stayton, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600396/
https://ncbi.nlm.nih.gov/pubmed/23075320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300338s
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