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Intracellular delivery and trafficking dynamics of a lymphoma-targeting antibody-polymer conjugate
Ratiometric fluorescence and cellular fractionation studies were employed to characterize the intracellular trafficking dynamics of antibody-poly(propylacrylic acid) (PPAA) conjugates in CD22+ RAMOS-AW cells. The HD39 monoclonal antibody (mAb) directs CD22-dependent, receptor-mediated uptake in huma...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600396/ https://ncbi.nlm.nih.gov/pubmed/23075320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300338s |
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