Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells

The therapeutic potential of RNA interference (RNAi) has been limited by inefficient delivery of short interfering RNA (siRNA). Tumor-specific recognition can be effectively achieved by antibodies directed against highly expressed cancer cell surface receptors. We investigated the utility of linking...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Palanca-Wessels, Maria C., Booth, Garrett C., Convertine, Anthony J., Lundy, Brittany B., Berguig, Geoffrey Y., Press, Michael F., Stayton, Patrick S., Press, Oliver W.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891060/
https://ncbi.nlm.nih.gov/pubmed/26840082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7076
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker