Athero-Inflammatory Nanotherapeutics: Ferulic Acid-based Poly(anhydride-ester) Nanoparticles Attenuate Foam Cell Formation by Regulating Macrophage Lipogenesis and Reactive Oxygen Species Generation

Enhanced bioactive anti-oxidant formulations are critical for treatment of inflammatory diseases, such as atherosclerosis. A hallmark of early atherosclerosis is the uptake of oxidized low density lipoprotein (oxLDL) by macrophages, which results in foam cell and plaque formation in the arterial wal...

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Udgivet i:Acta Biomater
Main Authors: Chmielowski, Rebecca A., Abdelhamid, Dalia S., Faig, Jonathan J., Petersen, Latrisha K., Gardner, Carol R., Uhrich, Kathryn E., Joseph, Laurie B., Moghe, Prabhas V.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546209/
https://ncbi.nlm.nih.gov/pubmed/28522412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.05.029
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