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Nanotherapeutics Containing Lithocholic Acid-Based Amphiphilic Scorpion-Like Macromolecules Reduce In Vitro Inflammation in Macrophages: Implications for Atherosclerosis

Previously-designed amphiphilic scorpion-like macromolecule (AScM) nanoparticles (NPs) showed elevated potency to counteract oxidized low-density lipoprotein (oxLDL) uptake in atherosclerotic macrophages, but failed to ameliorate oxLDL-induced inflammation. We designed a new class of composite AScMs...

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Moretti, Alysha, Li, Qi, Chmielowski, Rebecca, Joseph, Laurie B., Moghe, Prabhas V., Uhrich, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853716/
https://ncbi.nlm.nih.gov/pubmed/29393918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8020084
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