P-gp Inhibition and Mitochondrial Impairment by Dual-Functional Nanostructure Based on Vitamin E Derivatives To Overcome Multidrug Resistance

Vitamin E derivatives possess many essential features for drug-delivery applications, such as biocompatibility, stability, improvement of water solubility of hydrophobic compounds, anticancer activity, and the ability to overcome multidrug resistance (MDR). Herein, vitamin E derivatives are used to...

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Publicat a:ACS Appl Mater Interfaces
Autors principals: Tuguntaev, Ruslan G., Chen, Shizhu, Eltahan, Ahmed Shaker, Mozhi, Anbu, Jin, Shubin, Zhang, Jinchao, Li, Chan, Wang, Paul C., Liang, Xing-Jie
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545886/
https://ncbi.nlm.nih.gov/pubmed/28463476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.7b03877
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