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The critical size of gold nanoparticles for overcoming P-gp mediated multidrug resistance
Multidrug resistance (MDR) remains a huge obstacle in cancer treatment. One of the most studied mechanisms of MDR is P-glycoprotein (P-gp) mediated drug efflux. Based on the three-dimensional structural characteristics of P-gp, gold nanoparticles (AuNPs) with an average size of 4.1 nm and 5.4 nm wer...
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| Publicat a: | Nanoscale |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7430045/ https://ncbi.nlm.nih.gov/pubmed/32790812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0nr03226c |
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