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Targeting tumor microenvironment with PEG-based amphiphilic nanoparticles to overcome chemoresistance

Multidrug resistance is one of the biggest obstacles in the treatment of cancer. Several factors involves in drug resistance including enhanced repair mechanisms of drug induced DNA damage, lowered tumor extracellular pH, alteration of cell cycle check points, blockage of apoptosis pathway, poor tum...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Chen, Shizhu, Yang, Keni, Tuguntaev, Ruslan G., Mozhi, Anbu, Zhang, Jinchao, Wang, Paul C., Liang, Xing-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789173/
https://ncbi.nlm.nih.gov/pubmed/26707818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.020
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