Targeting tumor microenvironment with PEG-based amphiphilic nanoparticles to overcome chemoresistance

Multidrug resistance is one of the biggest obstacles in the treatment of cancer. Several factors involves in drug resistance including enhanced repair mechanisms of drug induced DNA damage, lowered tumor extracellular pH, alteration of cell cycle check points, blockage of apoptosis pathway, poor tum...

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Bibliographic Details
Published in:	Nanomedicine
Main Authors:	Chen, Shizhu, Yang, Keni, Tuguntaev, Ruslan G., Mozhi, Anbu, Zhang, Jinchao, Wang, Paul C., Liang, Xing-Jie
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4789173/ https://ncbi.nlm.nih.gov/pubmed/26707818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.020
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Targeting tumor microenvironment with PEG-based amphiphilic nanoparticles to overcome chemoresistance

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