Targeting tumor microenvironment with PEG-based amphiphilic nanoparticles to overcome chemoresistance

Multidrug resistance is one of the biggest obstacles in the treatment of cancer. Several factors involves in drug resistance including enhanced repair mechanisms of drug induced DNA damage, lowered tumor extracellular pH, alteration of cell cycle check points, blockage of apoptosis pathway, poor tum...

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Pubblicato in:Nanomedicine
Autori principali: Chen, Shizhu, Yang, Keni, Tuguntaev, Ruslan G., Mozhi, Anbu, Zhang, Jinchao, Wang, Paul C., Liang, Xing-Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789173/
https://ncbi.nlm.nih.gov/pubmed/26707818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.020
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