Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors

Multifunctional enzymes glutathione transferases (GSTs) are involved in the development of chemoresistance, thus representing a promising target for a novel approach in cancer treatment. This superfamily of polymorphic enzymes exhibits extraordinary substrate promiscuity responsible for detoxificati...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Pljesa-Ercegovac, Marija, Savic-Radojevic, Ana, Matic, Marija, Coric, Vesna, Djukic, Tatjana, Radic, Tanja, Simic, Tatjana
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321424/
https://ncbi.nlm.nih.gov/pubmed/30487385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123785
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