Engineered Three-Dimensional Cardiac Fibrotic Tissue to Study Fibrotic Remodeling

Activation of cardiac fibroblasts (CF) into myofibroblasts is considered to play an essential role in cardiac remodeling and fibrosis. A limiting factor in studying this process is the spontaneous activation of CFs when cultured on two-dimensional (2D) culture plates. Here, a simplified 3D hydrogel...

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Bibliografiske detaljer
Udgivet i:Adv Healthc Mater
Main Authors: Sadeghi, Amir Hossein, Shin, Su Ryon, Deddens, Janine C., Fratta, Giuseppe, Mandla, Serena, Yazdi, Iman K., Prakash, Gyan, Antona, Silvia, Demarchi, Danilo, Buijsrogge, Marc P., Sluijter, Joost P.G., Hjortnaes, Jesper, Khademhosseini, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545804/
https://ncbi.nlm.nih.gov/pubmed/28498548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201601434
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