Engineered Three-Dimensional Cardiac Fibrotic Tissue to Study Fibrotic Remodeling

Activation of cardiac fibroblasts (CF) into myofibroblasts is considered to play an essential role in cardiac remodeling and fibrosis. A limiting factor in studying this process is the spontaneous activation of CFs when cultured on two-dimensional (2D) culture plates. Here, a simplified 3D hydrogel...

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Détails bibliographiques
Publié dans:Adv Healthc Mater
Auteurs principaux: Sadeghi, Amir Hossein, Shin, Su Ryon, Deddens, Janine C., Fratta, Giuseppe, Mandla, Serena, Yazdi, Iman K., Prakash, Gyan, Antona, Silvia, Demarchi, Danilo, Buijsrogge, Marc P., Sluijter, Joost P.G., Hjortnaes, Jesper, Khademhosseini, Ali
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545804/
https://ncbi.nlm.nih.gov/pubmed/28498548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201601434
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