Engineered Three-Dimensional Cardiac Fibrotic Tissue to Study Fibrotic Remodeling

Activation of cardiac fibroblasts (CF) into myofibroblasts is considered to play an essential role in cardiac remodeling and fibrosis. A limiting factor in studying this process is the spontaneous activation of CFs when cultured on two-dimensional (2D) culture plates. Here, a simplified 3D hydrogel...

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Publicat a:Adv Healthc Mater
Autors principals: Sadeghi, Amir Hossein, Shin, Su Ryon, Deddens, Janine C., Fratta, Giuseppe, Mandla, Serena, Yazdi, Iman K., Prakash, Gyan, Antona, Silvia, Demarchi, Danilo, Buijsrogge, Marc P., Sluijter, Joost P.G., Hjortnaes, Jesper, Khademhosseini, Ali
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545804/
https://ncbi.nlm.nih.gov/pubmed/28498548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201601434
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