Engineered Three-Dimensional Cardiac Fibrotic Tissue to Study Fibrotic Remodeling

Activation of cardiac fibroblasts (CF) into myofibroblasts is considered to play an essential role in cardiac remodeling and fibrosis. A limiting factor in studying this process is the spontaneous activation of CFs when cultured on two-dimensional (2D) culture plates. Here, a simplified 3D hydrogel...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Sadeghi, Amir Hossein, Shin, Su Ryon, Deddens, Janine C., Fratta, Giuseppe, Mandla, Serena, Yazdi, Iman K., Prakash, Gyan, Antona, Silvia, Demarchi, Danilo, Buijsrogge, Marc P., Sluijter, Joost P.G., Hjortnaes, Jesper, Khademhosseini, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545804/
https://ncbi.nlm.nih.gov/pubmed/28498548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201601434
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