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Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

Dynamic remodeling of the extracellular matrix (ECM) is essential for development, wound healing and normal organ homeostasis. Life-threatening pathological conditions arise when ECM remodeling becomes excessive or uncontrolled. In this Perspective, we focus on how ECM remodeling contributes to fibr...

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Detalhes bibliográficos
Main Authors: Cox, Thomas R., Erler, Janine T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046088/
https://ncbi.nlm.nih.gov/pubmed/21324931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.004077
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