Local DNA repair inhibition for sustained radiosensitization of high grade gliomas

High-grade gliomas such as glioblastoma (GBM) and diffuse intrinsic pontine glioma (DIPG) are characterized by an aggressive phenotype with nearly universal local disease progression despite multimodal treatment, which typically includes chemotherapy, radiation therapy (RT), and possibly surgery. Ra...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: King, Amanda R., Corso, Christopher D., Chen, Evan M., Song, Eric, Bongiorni, Paul, Chen, Zhe, Sundaram, Ranjini K., Bindra, Ranjit S., Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545124/
https://ncbi.nlm.nih.gov/pubmed/28566437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0788
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