Local DNA repair inhibition for sustained radiosensitization of high grade gliomas

High-grade gliomas such as glioblastoma (GBM) and diffuse intrinsic pontine glioma (DIPG) are characterized by an aggressive phenotype with nearly universal local disease progression despite multimodal treatment, which typically includes chemotherapy, radiation therapy (RT), and possibly surgery. Ra...

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Опубликовано в: :Mol Cancer Ther
Главные авторы: King, Amanda R., Corso, Christopher D., Chen, Evan M., Song, Eric, Bongiorni, Paul, Chen, Zhe, Sundaram, Ranjini K., Bindra, Ranjit S., Saltzman, W. Mark
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545124/
https://ncbi.nlm.nih.gov/pubmed/28566437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0788
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