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Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity
Autoimmunity is largely prevented by medullary thymic epithelial cells (TECs) through their expression and presentation of tissue-specific Ags to developing thymocytes, resulting in deletion of self-reactive T cells and supporting regulatory T cell development. The transcription factor Prdm1 has bee...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AAI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5544928/ https://ncbi.nlm.nih.gov/pubmed/28701508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600941 |
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