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TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles
TRPM7 (transient receptor potential cation channel subfamily M member 7) regulates gene expression and stress-induced cytotoxicity and is required in early embryogenesis through organ development. Here, we show that the majority of TRPM7 is localized in abundant intracellular vesicles. These vesicle...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5544332/ https://ncbi.nlm.nih.gov/pubmed/28696294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707380114 |
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