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Histone phosphorylation by TRPM6’s cleaved kinase attenuates adjacent arginine methylation to regulate gene expression

TRPM6 and TRPM7 are members of the melastatin-related transient receptor potential (TRPM) subfamily of ion channels. Deletion of either gene in mice is embryonically lethal. TRPM6/7 are the only known examples of single polypeptides containing both an ion channel pore and a serine/threonine kinase (...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Krapivinsky, Grigory, Krapivinsky, Luba, Renthal, Nora E., Santa-Cruz, Ana, Manasian, Yunona, Clapham, David E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576826/
https://ncbi.nlm.nih.gov/pubmed/28784805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708427114
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