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TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles

TRPM7 (transient receptor potential cation channel subfamily M member 7) regulates gene expression and stress-induced cytotoxicity and is required in early embryogenesis through organ development. Here, we show that the majority of TRPM7 is localized in abundant intracellular vesicles. These vesicle...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Abiria, Sunday A., Krapivinsky, Grigory, Sah, Rajan, Santa-Cruz, Ana G., Chaudhuri, Dipayan, Zhang, Jin, Adstamongkonkul, Pichet, DeCaen, Paul G., Clapham, David E.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544332/
https://ncbi.nlm.nih.gov/pubmed/28696294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707380114
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