G9a coordinates with the RPA complex to promote DNA damage repair and cell survival

Histone methyltransferase G9a has critical roles in promoting cancer-cell growth and gene suppression, but whether it is also associated with the DNA damage response is rarely studied. Here, we report that loss of G9a impairs DNA damage repair and enhances the sensitivity of cancer cells to radiatio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Qiaoyan, Zhu, Qian, Lu, Xiaopeng, Du, Yipeng, Cao, Linlin, Shen, Changchun, Hou, Tianyun, Li, Meiting, Li, Zhiming, Liu, Chaohua, Wu, Di, Xu, Xingzhi, Wang, Lina, Wang, Haiying, Zhao, Ying, Yang, Yang, Zhu, Wei-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544285/
https://ncbi.nlm.nih.gov/pubmed/28698370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700694114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados