The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2

Cyclooxygenase-2 (COX-2) is overexpressed in a variety of human epithelial cancers, including lung cancer, and is highly associated with a poor prognosis and a low survival rate. Understanding how COX-2 is regulated in response to carcinogens will offer insight into designing anti-cancer strategies...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lu, Shaoli, Yang, Yang, Du, Yipeng, Cao, Lin-lin, Li, Meiting, Shen, Changchun, Hou, Tianyun, Zhao, Ying, Wang, Haiying, Deng, Dajun, Wang, Lina, He, Qihua, Zhu, Wei-Guo
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741484/
https://ncbi.nlm.nih.gov/pubmed/26430963
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