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Internalization of blocking antibodies against mannose-6-phosphate specific receptors.

Antibodies against mannose-6-phosphate specific receptors inhibit the receptor-dependent endocytosis of exogenous lysosomal enzymes as well as the sorting of endogenous lysosomal enzymes. This inhibition was correlated with an apparent loss of the receptors. We report here that treatment of cells wi...

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Autori principali: Gartung, C, Braulke, T, Hasilik, A, von Figura, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC554409/
https://ncbi.nlm.nih.gov/pubmed/3161725
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